Naohiko Takahashi Selected Research

dihydrolipoylhistidine

3/2011

New lipoic acid derivative drug sodium zinc dihydrolipoylhistidinate prevents cardiac dysfunction in an isolated perfused rat heart model.

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Naohiko Takahashi Research Topics

Disease

33	Atrial Fibrillation 03/2024 - 11/2007
22	Heart Failure 03/2024 - 07/2010
18	Fibrosis (Cirrhosis) 04/2023 - 11/2007
17	Insulin Resistance 01/2023 - 09/2003
13	Reperfusion Injury 01/2016 - 10/2002
10	Ischemia 03/2011 - 10/2002
8	Type 2 Diabetes Mellitus (MODY) 01/2023 - 10/2004
8	Hyperthermia 01/2012 - 08/2006
7	Cardiac Arrhythmias (Arrythmia) 12/2022 - 08/2005
7	Hemorrhage 06/2022 - 08/2015
7	Heart Diseases (Heart Disease) 07/2020 - 09/2008
7	Inflammation (Inflammations) 01/2019 - 10/2011
6	Ventricular Tachycardia 01/2011 - 11/2003
4	Sarcoidosis (Schaumann Disease) 04/2024 - 04/2012
4	Aortic Valve Stenosis (Aortic Stenosis) 03/2024 - 06/2022
4	Cardiac Sudden Death (Sudden Cardiac Arrest) 03/2024 - 08/2014
4	Tachycardia (Tachyarrhythmias) 03/2023 - 07/2003
4	Brugada Syndrome 02/2021 - 08/2014
4	Ventricular Fibrillation 11/2020 - 08/2014
4	Infarction (Infarctions) 10/2019 - 05/2009
4	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 02/2007 - 09/2003
3	Hypoxia (Hypoxemia) 11/2018 - 05/2006
3	Obesity 01/2018 - 09/2008
3	Coronary Artery Disease (Coronary Atherosclerosis) 10/2014 - 03/2004
3	Diabetes Mellitus 10/2014 - 05/2012
3	Myocardial Infarction 01/2011 - 02/2009
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2024 - 09/2008
2	Bundle-Branch Block (Fascicular Block) 12/2023 - 10/2005
2	Myocardial Ischemia (Ischemic Heart Diseases) 12/2023 - 03/2009
2	Chronic Renal Insufficiency 01/2023 - 01/2012
2	Syncope (Fainting) 05/2022 - 11/2020
2	Shock 02/2021 - 08/2014
2	Thromboembolism 02/2021 - 08/2015
2	Hypothermia 01/2021 - 01/2019
2	Spasm (Spasms) 12/2020 - 01/2018
2	Hyperglycemia 07/2020 - 01/2016
2	Atrial Remodeling 01/2018 - 01/2016
2	Stroke (Strokes) 01/2011 - 07/2010
2	Chronic Kidney Failure (Chronic Renal Failure) 05/2007 - 05/2006

Drug/Important Bio-Agent (IBA)

17	Insulin (Novolin)FDA Link 01/2023 - 10/2002
10	HSP72 Heat-Shock ProteinsIBA 12/2011 - 07/2003
7	Angiotensin IIIBA 12/2020 - 06/2004
7	Glucose (Dextrose)FDA LinkGeneric 07/2020 - 07/2005
5	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019 - 07/2010
5	Streptozocin (Streptozotocin)FDA Link 01/2019 - 10/2002
5	geranylgeranylacetone (teprenone)IBA 12/2009 - 07/2003
4	edoxabanIBA 01/2022 - 01/2019
4	Anti-Arrhythmia AgentsIBA 11/2018 - 01/2011
4	Pioglitazone (Actos)FDA Link 01/2012 - 08/2006
3	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 04/2023 - 01/2016
3	CytokinesIBA 04/2023 - 01/2018
3	Biomarkers (Surrogate Marker)IBA 01/2023 - 02/2021
3	C-Reactive ProteinIBA 01/2020 - 04/2005
3	AnticoagulantsIBA 01/2020 - 08/2015
3	Interleukin-10 (Interleukin 10)IBA 01/2019 - 01/2016
3	AntioxidantsIBA 12/2012 - 03/2011
3	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2012 - 07/2005
3	Phosphatidylinositols (Phosphatidylinositol)IBA 12/2011 - 08/2006
3	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 12/2011 - 08/2006
3	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2011 - 02/2009
3	Creatine Kinase (Creatine Phosphokinase)IBA 05/2009 - 11/2003
2	ElectrolytesIBA 04/2024 - 10/2019
2	omega-Chloroacetophenone (Mace)IBA 01/2024 - 07/2010
2	Interleukin-6 (Interleukin 6)IBA 04/2023 - 09/2008
2	Conditioned Culture MediaIBA 04/2023 - 01/2020
2	Angiopoietin-Like Protein 2IBA 04/2023 - 01/2020
2	CollagenIBA 04/2023 - 10/2014
2	ChemokinesIBA 04/2023 - 11/2018
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2023 - 01/2016
2	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2023 - 07/2005
2	Protein Kinase CIBA 10/2020 - 11/2003
2	Proteins (Proteins, Gene)FDA Link 01/2020 - 04/2003
2	SodiumIBA 10/2019 - 03/2011
2	pilsicainideIBA 08/2017 - 05/2007
2	LeptinIBA 06/2017 - 04/2013
2	salicylhydroxamic acid (SHAM)IBA 03/2017 - 01/2016
2	Bepridil (Vascor)FDA Link 12/2016 - 08/2014
2	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2016 - 10/2015
2	Collagen Type I (Type I Collagen)IBA 10/2015 - 10/2014
2	ResveratrolIBA 07/2012 - 04/2003
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 01/2012 - 02/2011
2	candesartanIBA 12/2011 - 06/2004
2	AdiponectinIBA 10/2011 - 07/2007
2	CalciumIBA 01/2011 - 03/2004
2	Pravastatin (Pravachol)FDA LinkGeneric 01/2011 - 06/2010
2	mitochondrial K(ATP) channelIBA 05/2009 - 09/2007
2	AdrenomedullinIBA 03/2009 - 06/2005
2	HDL CholesterolIBA 07/2007 - 02/2007

Therapy/Procedure

19	Catheter Ablation 04/2023 - 07/2003
14	Therapeutics 12/2023 - 07/2005
11	Implantable Defibrillators (Implantable Cardioverter-Defibrillator) 03/2024 - 08/2014
10	Cardiac Resynchronization Therapy 03/2024 - 10/2011
4	Percutaneous Coronary Intervention 08/2023 - 01/2011
3	Transcatheter Aortic Valve Replacement 03/2024 - 06/2022
3	Drug Therapy (Chemotherapy) 12/2023 - 10/2022
3	Patient Readmission 06/2022 - 01/2020
2	Catheters 02/2023 - 06/2022
2	Rewarming 01/2021 - 01/2019
2	Defibrillators (Defibrillator) 02/2015 - 08/2005
2	Renal Dialysis (Hemodialysis) 05/2007 - 05/2006